I've had some success while impaired. However, I really try to play certain games only. I never play cash games, especially NL. I do the 5 and 10 SnGs and play loose/maniac for fun against weaker players for the most part.

And if I have enough sense about me (i.e. partially impaired), I'll try to cultivate a table image and then suddenly start playing opposite of that. I'll also try all the tools available like checkraise bluff, overbetting, etc.

It would be nice though if I could remember what worked and what didn't.