for NLHE cash games..
22-77..
just limp in and try to hit a set..
if someone raises and he has more money at the table then 7x his raise.. then call and try to hit a set.. so basically just play them for set value.. if any overcards hits the flop then its pretty much check-fold..

personally for me, i tend to play 22-88, and sometimes 99 this way as well...
because i find that pocket 8s and pocket 9s.. sometimes even pocket jacks and tens.. are EXTREMELY hard to play after the flop, when u get a few callers, and thers over cards on the flop.