Pokeroffice I think is better if you are a beginner, as some of the features can really help you play. Getting realtime pot odds, and realtime draw odds are good if you haven't memorized them.

Other than that, I find that Pokertracker is a much, much better product. There is alot more options and the support is alot better, not to mention constant updates, alot of new sites are constantly added and they offer support to alot more networks.

Besides for beginners the only thing PO has going for it over PT is that it supports the iPoker network.